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ShARM is a not for profit organisation, open to all scientific investigators in the UK and overseas, aiming to accelerate research into ageing by facilitating the sharing of resources. ShARM provides immediate and cost effective access to aged murine models and their tissue through a biorepository and database of live ageing colonies. ShARM also promotes the networking of researchers and dissemination of knowledge through its online collaborative environment; MiCEPACE.

ShARM is funded by Wellcome Trust and works in partnership with MRC Harwell and the Centre for Intergrated Research into Musculoskeletal Ageing (CIMA).

Tissues currently available from mice:

    Female Male
Tissue   aged < 3 months aged > 18 months aged > 18 months
BAT   10 16 82
Bladder     6 45
Bone (misc)   10 16 45
Brain   10 16 67
Femur Left   6 43
Femur Right   6 43
Gut Duodenum 10 16 69
Gut Jejunum   6 43
Gut Ileum   6 43
Gut Cecum   6 43
Gut Colon   6 43
Heart   10 16 87
Kidney Left 10 16 87
Kidney Right 10 10 84
Liver Left 10 16 86
Liver Right 10 16 50
Liver Median   6 43
Liver Caudate   6 43
Lung Left 10 4 2
Lung Right 10 4 2
Lung Whole   6 85
Mammary fat   1 11 43
Muscle   10 16 63
Pancreas     6 75
Skin   10 16 87
Spleen   10 10 84
Thymus   10 16 50
Thyroid     6 43
Tibia Left   6 43
Tibia Right   6 43
WAT   10 16 85

 

For the acquisition, storage and provision of flash frozen, aged murine tissue. Samples are derived from a range of models and ages with an online inventory and young controls available. Online searchable database of current, live ageing colonies. Colony owners are invited to register their colony for addition to the database and are introduced to investigators able to use surplus tissue.

The online collaborative environment for researchers to interact, network and collaborate. MiCEPACE includes: 
Forums, articles, protocols and instructional videos.

 

Statement on behalf of BBSRC & MRC

 "ShARM will provide valuable resources for the scientific community while helping to reduce the number of animals used in vital research into ageing.  The biobank of tissue and networking facility will enable scientists to access shared research material and data.  By making use of collective resources, the number of individual animals required in research experiments can be minimised. The project also has the added value of helping to reduce the costs of research by connecting scientists, pooling resource and combining knowledge."

 

 

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